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KMID : 0381120150370020135
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Genes and Genomics
2015 Volume.37 No. 2 p.135 ~ p.140
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Composition and evolutionary importance of transposable elements in humans and primates
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Lee Hee-Eun
Eo Jung-Woo
Kim Heui-Soo
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Abstract
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Transposable elements (TEs) have skill of altering the position inside the genome and these TEs are widespread in both of plants and animals. They are separated into class I called retrotransposons, and class II called DNA transposons. According to the previous studies, not only TEs are related with disease, they are key factor of human and primate evolution. From this review, we discussed about the impact of transposable element, its role in the genome of human and primates and how TE distribution is differ from them. Additionally, we described how TEs contributed on primate evolution by its unique role. This review could be great use for further studies in relation to evolution mechanism and various diseases.
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KEYWORD
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Transposable elements, Humans, Primates, Evolution, Disease
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